Check the B12 form and the amount per serving, which is usually listed in micrograms. Because the amounts in supplements vary widely, measure the powder carefully and follow the label. People with absorption concerns should discuss their B12 status and supplement form with a healthcare professional.
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Vitamin B12 is a water-soluble nutrient also called cobalamin. Supplement labels may list forms such as cyanocobalamin or methylcobalamin; NIH notes that research has not shown one supplemental form to be better than the others.
Vitamin B12 helps maintain healthy blood and nerve cells and is needed to make DNA. It supports normal energy metabolism, but supplemental B12 has not been shown to boost energy or endurance in people who already get enough.